The Protocol That Moved the Biological Clock Backward | TruDiagnostic Podcast

Dr. Chris ShadeApr 15, 2026

Aging isn’t just about time. It’s about toxic exposure, mitochondrial dysfunction, and impaired cellular processes that accelerate biological decline long before the symptoms become visible.
Dr. Christopher Shade joins Hannah Went of TruDiagnostic to break down why effective longevity strategies have to start with detoxification — and what happens when they do. Dr. Shade walks through his multi-phase approach: first removing toxins and activating key pathways like NRF2, then enhancing metabolic and mitochondrial function through AMPK and NAD support. The conversation covers a clinical study in which this protocol improved biological aging markers, and explores how detox, metabolism, immunity, and hormone health are interconnected — with toxic burden sitting at the root of nearly all of them.

Dr. Shade’s Protocols

Weekly deep dives into real health problems, decoded through chemistry and systems biology. Each issue breaks down the catalyst, the mechanism, and the protocol that actually works.