Free Medicine & Supplements That Work | Stacked with Joe DiStefano – Runga

Dr. Chris ShadeMay 28, 2026

Discussing metabolism, longevity, and cellular health, Dr. Christopher Shade explores the science behind ketosis, intermittent fasting, detoxification, and energy production. The discussion reveals how pathways like AMPK and ketone metabolism influence sleep, resilience, and overall wellness, while connecting gut health, oxidative stress, glutathione, and recovery into a practical framework for optimizing health, enhancing vitality, and navigating today’s increasingly complex wellness landscape.

IN THIS EPISODE:
5:49 Stess and Detoxification
8:09 Free Medicine
10:00 Risk of Stress
13:01 Micro Retreats
17:29 Toxicity
20:14 Health of the Cell
26:13 Canaliculi Trafficking
29:29 MPK
36:36 Plant Based Diet
38:43 Mitochondria
42:55 Quicksilver
50:12 Why We Preferentialy Go To Carbohydrate Metabolism
52:42 The Supplement Industry

Dr. Shade’s Protocols

Weekly deep dives into real health problems, decoded through chemistry and systems biology. Each issue breaks down the catalyst, the mechanism, and the protocol that actually works.